io.github.cyanheads/ensembl-mcp-server

io.github.cyanheads/ensembl-mcp-server

Look up genes, sequences, variants, homologs, and cross-database xrefs from Ensembl REST.

Connect this server

Add this to your MCP client config — claude_desktop_config.json (Claude Desktop) or .cursor/mcp.json (Cursor).Suits: Claude Desktop · Cursor.

{
  "mcpServers": {
    "ensembl-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/ensembl-mcp-server@0.7.1"
      ],
      "env": {
        "ENSEMBL_BASE_URL": "https://rest.ensembl.org",
        "MCP_LOG_LEVEL": "info"
      }
    }
  }
}
Environment variables
  • ENSEMBL_BASE_URLEnsembl REST API base URL. Override to use GRCh37 endpoint or a local mirror.
  • MCP_LOG_LEVELSets the minimum log level for output (e.g., 'debug', 'info', 'warn').

A starting point — check the repository for exact arguments and setup. Restart your client after editing the config.

Category
Developer Tools
Version
0.7.1
Registry
active
Published
10/29/2026

Remotes

  • streamable-httphttps://ensembl.caseyjhand.com/mcp
Browse all Developer Tools →

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